John Krasinski John Hollar Margo Martindale Sally Hollar Richard Jenkins Don Hollar Sharlto Copley Ron Hollar Anna Kendrick Rebecca Charlie Day Jason Mary Elizabeth Winstead Gwen Randall Park Dr. Fong Josh Groban Reverend Dan Mary Kay Place Pam Ashley Dyke Stacey Didi Costine Matilda Isabela Costine Constance Nancy Nave OB Nurse Yvonne Angulo ER Nurse Tonea Stewart Latisha Gus Sanchez Pedro Kristin Scoggins ICU Nurse #4 Hillary Schoelzel ER Nurse #2 Emma Frances Burge Airport Traveler (uncredited) Travis Turner Doctor (uncredited) Lamar Lott Bank Patron (uncredited) Aaron J. Brooks Plane Passenger (uncredited) Brady Permenter Boy on Bike (uncredited)