Dan Aykroyd Louis Winthorpe III Eddie Murphy Billy Ray Valentine Ralph Bellamy Randolph Duke Don Ameche Mortimer Duke Denholm Elliott Coleman Kristin Holby Penelope Witherspoon Paul Gleason Clarence Beeks Jamie Lee Curtis Ophelia Alfred Drake President of Exchange Bo Diddley Pawnbroker Frank Oz Corrupt Cop Jim Belushi Harvey Al Franken Baggage Handler #1 Tom Davis Baggage Handler #2 Walt Gorney Duke Domestic Tom Mardirosian Officer Pantuzzi Robert Curtis Brown Todd Nicholas Guest Harry John Bedford Lloyd Andrew Robert Earl Jones Attendant Clint Smith Doo Rag Lenny Ron Taylor Big Black Guy Giancarlo Esposito Cellmate #2 Steve Hofvendahl Cellmate #3 James Eckhouse Guard Eddie Jones Cop #3 Michelle Mais Hooker #1 Bill Cobbs Bartender Kelly Curtis Muffy Philip Bosco Doctor Richard Hunt Wilson Afemo Omilami Longshoreman Barry Dennen Demitri Charles Pendelton Cop (uncredited) Dan Aykroyd Louis Winthorpe III Eddie Murphy Billy Ray Valentine Ralph Bellamy Randolph Duke Don Ameche Mortimer Duke Denholm Elliott Coleman Kristin Holby Penelope Witherspoon Paul Gleason Clarence Beeks Jamie Lee Curtis Ophelia Alfred Drake President of Exchange Bo Diddley Pawnbroker Frank Oz Corrupt Cop Jim Belushi Harvey Al Franken Baggage Handler #1 Tom Davis Baggage Handler #2 Walt Gorney Duke Domestic Tom Mardirosian Officer Pantuzzi Robert Curtis Brown Todd Nicholas Guest Harry John Bedford Lloyd Andrew Robert Earl Jones Attendant Clint Smith Doo Rag Lenny Ron Taylor Big Black Guy Giancarlo Esposito Cellmate #2 Steve Hofvendahl Cellmate #3 James Eckhouse Guard Eddie Jones Cop #3 Michelle Mais Hooker #1 Bill Cobbs Bartender Kelly Curtis Muffy Philip Bosco Doctor Richard Hunt Wilson Jack Davidson Trader #3 Bernie McInerney Trader #4 Ralph Clanton Official #1 Gary Klar Longshoreman Afemo Omilami Longshoreman Barry Dennen Demitri Benjean Stray Dog (uncredited) John Black Man Sitting on Couch at Party (uncredited) John Landis Man with Briefcase (uncredited) Charles Pendelton Cop (uncredited) Arleen Sorkin Woman at Party (uncredited) Marlene Willoughby Woman Passed Out on Couch (uncredited) Dan Aykroyd Louis Winthorpe III Eddie Murphy Billy Ray Valentine Ralph Bellamy Randolph Duke Don Ameche Mortimer Duke Denholm Elliott Coleman Kristin Holby Penelope Witherspoon Paul Gleason Clarence Beeks Jamie Lee Curtis Ophelia Alfred Drake President of Exchange Bo Diddley Pawnbroker Frank Oz Corrupt Cop Jim Belushi Harvey Al Franken Baggage Handler #1 Tom Davis Baggage Handler #2 Walt Gorney Duke Domestic Tom Mardirosian Officer Pantuzzi Robert Curtis Brown Todd Nicholas Guest Harry John Bedford Lloyd Andrew Robert Earl Jones Attendant Clint Smith Doo Rag Lenny Ron Taylor Big Black Guy Giancarlo Esposito Cellmate #2 Steve Hofvendahl Cellmate #3 James Eckhouse Guard Eddie Jones Cop #3 Michelle Mais Hooker #1 Bill Cobbs Bartender Kelly Curtis Muffy Philip Bosco Doctor Richard Hunt Wilson Jack Davidson Trader #3 Bernie McInerney Trader #4 Ralph Clanton Official #1 Gary Klar Longshoreman Afemo Omilami Longshoreman Barry Dennen Demitri Benjean Stray Dog (uncredited) John Black Man Sitting on Couch at Party (uncredited) John Landis Man with Briefcase (uncredited) Charles Pendelton Cop (uncredited) Arleen Sorkin Woman at Party (uncredited) Marlene Willoughby Woman Passed Out on Couch (uncredited)