Au printemps 1940, Mussolini a déclaré la guerre à la France et à la Grande-Bretagne. La ville sicilienne de Castelcuto est en liesse. Renato Amoroso, un garçon de treize ans, est heureux pour d'autres raisons. Il vient de recevoir sa première bicyclette et de tomber sous le charme de Malena, une ravissante veuve de guerre qui fait tourner la tête à tous les hommes du village et attise la haine des épouses jalouses. Renato, littéralement envoûté, la suit partout avec son vélo. Mais Malena est victime des refoulements et des convoitises des habitants de Castelcuto. Le petit garçon va trouver le moyen de l'aider, et grâce à elle, il apprendra les leçons de la vie. On the day in 1940 that Italy enters the war, two things happen to the 12-year-old Renato: he gets his first bike, and he gets his first look at Malèna. She is a beautiful, silent outsider who's moved to this Sicilian town to be with her husband, Nico. He promptly goes off to war, leaving her to the lustful eyes of the men and the sharp tongues of the women. During the next few years, as Renato grows toward manhood, he watches Malèna suffer and prove her mettle. He sees her loneliness, then grief when Nico is reported dead, the effects of slander on her relationship with her father, her poverty and search for work, and final humiliations. Will Renato learn courage from Malèna and stand up for her?