Hayden Christensen Ben (segment "Jiang Wen") Andy García Garry (segment "Jiang Wen") Rachel Bilson Molly (segment "Jiang Wen") Natalie Portman Rifka Malone (segment Mira Nair) Irrfan Khan Mansukhbhai (segment Mira Nair) Orlando Bloom David Cooler (segment "Shunji Iwai") Christina Ricci Camille (segment "Shunji Iwai") Maggie Q Janice Taylor (segment "Yvan Attal") Ethan Hawke Writer (segment "Yvan Attal") Chris Cooper Alex (segment "Yvan Attal") Robin Wright Anna (segment "Yvan Attal") Anton Yelchin Boy (segment "Brett Ratner") James Caan Mr. Riccoli (segment "Brett Ratner") Olivia Thirlby Actress (segment "Brett Ratner") Blake Lively Gabrielle DiMarco (segment "Brett Ratner") Drea de Matteo Lydia (segment "Allen Hughes") Bradley Cooper Gus (segment "Allen Hughes") Julie Christie Isabelle (segment "Shekhar Kapur") John Hurt Bellhop (segment "Shekhar Kapur") Shia LaBeouf Jacob (segment "Shekhar Kapur") Carlos Acosta Dante (segment "Natalie Portman") Jacinda Barrett Maggie (segment "Natalie Portman") Uğur Yücel Painter (segment "Fatih Akin") Shu Qi Chinese Herbalist (segment "Fatih Akin") Burt Young Landlord (segment "Fatih Akin") Eli Wallach Abe (segment "Joshua Marston") Cloris Leachman Mitzie (segment "Joshua Marston") Eva Amurri Martino Sarah (segment "Randy Balsmeyer") Justin Bartha Justin (segment "Randy Balsmeyer") Juri Henley-Cohn Ali (Transitions) Gurdeep Singh Badal (Transitions) Emory Cohen Prom Date (segment "Brett Ratner") Nicholas Purcell Boy (uncredited)