Warren Beatty Howard Hughes Lily Collins Marla Mabrey Alden Ehrenreich Frank Forbes Matthew Broderick Levar Mathis Annette Bening Lucy Mabrey Alec Baldwin Bob Maheu Haley Bennett Mamie Murphy Candice Bergen Nadine Henly Dabney Coleman Raymond Holliday Ed Harris Mr. Bransford Martin Sheen Noah Dietrich Paul Sorvino Vernon Scott Oliver Platt Forester Amy Madigan Mrs. Bransford Taissa Farmiga Sarah Bransford Michael Badalucco Solly Steve Coogan Colonel Nigel Briggs Megan Hilty Sally Paul Schneider Richard Miskin Chace Crawford Young Actor Eileen Ryan Frank's Grandmother Patrick Fischler Director Ron Perkins Senator Ferguson Peter MacKenzie Gene Handsaker Julio Oscar Mechoso President Somoza Hart Bochner Colonel Willis Caitlin Carver Marla Lookalike Evan O'Toole Matt Mabrey Holmes Osborne Cappy Steven Mnuchin Merrill Lynch Executive Ivar Brogger T.V. Newsman #1 Steve Tom TV Newsman #2 Dan Desmond Gladwin Hill Louise Linton Betty Christine Marzano Carrie Graham Beckel Wilbur James Keane Tom Bruce Gray Baptist Preacher Marshall Bell Colonel Maxwell Kyle Bornheimer Concerned Orderly Geoff Pierson Merrill Lynch Executive Michael Badalucco Solly the Barber James Gleason Doctor Crone James Martin Kelly Mobster