Michael J. Fox Stuart Little (voice) Geena Davis Mrs. Eleanor Little Hugh Laurie Mr. Fredrick Little Jonathan Lipnicki George Little Nathan Lane Snowbell (voice) Steve Zahn Monty (voice) Chazz Palminteri Smokey (voice) David Alan Grier Red (voice) Jennifer Tilly Camille Stout (voice) Jim Doughan Det. Phil Allen / Lucky (voice) Bruno Kirby Reginald Stout (voice) Stan Freberg Race Announcer (voice) Jeffrey Jones Crenshaw Little Connie Ray Tina Little Allyce Beasley Beatrice Little Brian Doyle-Murray Edgar Little Estelle Getty Estelle Little Harold Gould Spencer Little Patrick Thomas O'Brien Uncle Stretch Julia Sweeney Mrs. Keeper Dabney Coleman Dr. Beechwood