Kaleb est un jeune adulte qui vit de petits boulots. Fasciné par les animaux exotiques, il trouve une araignée venimeuse dans un bazar et la ramène dans son appartement. Il ne lui faut qu'un instant pour s'échapper et se reproduire, transformant l'endroit en un terrible piège en toile. A Seule option pour Kaleb et ses amis : trouver la sortie, survivre. Kaleb is about to turn 30 and has never been lonelier. He’s fighting with his sister over their inheritance and has cut ties with his best friend. Passionate about exotic animals, he comes home one day with an unusual spider and accidentally lets it slip away. Soon his underprivileged suburb is thrown into chaos as the deadly arachnids multiply. Ordered to be placed under quarantine, the project's inhabitants are forced to live in lockdown alongside terrifying spiders that are becoming bigger and bigger.