Seth Rogen Frank / Sergeant Pepper (voice) Kristen Wiig Brenda (voice) Jonah Hill Carl (voice) Bill Hader Firewater / Tequila / El Guaco (voice) Michael Cera Barry (voice) James Franco Druggie (voice) Danny McBride Honey Mustard (voice) Craig Robinson Grits (voice) Paul Rudd Darren (voice) Nick Kroll Douche (voice) David Krumholtz Kareem Abdul Lavash (voice) Edward Norton Sammy Bagel Jr. (voice) Salma Hayek Pinault Teresa Taco (voice) Anders Holm Troy (voice) Scott Underwood Gum / Twink / Krinkler's Chips / Pizza (voice) Sugar Lyn Beard Baby Carrot / Cookies (voice) Conrad Vernon Toilet Paper / Sauerkraut / Catcall Sausage / Grape #1 / Beer Can / Pop Bottle (voice) Ian James Corlett Apple / Tickilish Licorice / Relish / Bag of Dog Food (voice) Michael Daingerfield Chunk Munchers Cereal / Light Bulb / Indian Chutney (voice) Jason Simpson Plum #2 / Beer Keg / Fat Guy / Fit Man (voice) Vincent Tong Pislitz Chips / Juice Box / Jamaican Rum (voice) Lauren Miller Camille Toh / Tampon (voice) Sam Vincent Old Pork Sausage / Refried Beans / Sandwich / Pop Tart / Licorice Rope (voice) Greg Tiernan Potato / Noodle Soup (voice) Brian Dobson Italian Tomato / Lettuce (voice) Harland Williams Ketchup / Drug Dealer / Baba Ganoush (voice) Alistair Abell Mariachi Salsa / Gefilte Fish (voice) Iris Apatow Berry Good Candies / Grape #3 / Coconut Milk (voice) Michael Dobson Queso (voice) Ian Hanlin Beet (voice) Maryke Hendrikse Popped Cherry Mixer / Plum #1 / Loretta Bun / Frozen Fruitz (voice) Nicole Oliver Sally Bun / Ice Cream / Watermelon / Female Shopper #1 (voice) Kelly Sheridan Roberta Bun / Grape #2 / Female Shopper #2 (voice) Meat Loaf Meatloaf (voice) (uncredited)