Rufus Sewell John Murdoch William Hurt Inspector Frank Bumstead Kiefer Sutherland Dr. Daniel P. Schreber Jennifer Connelly Emma Murdoch Richard O'Brien Mr. Hand Ian Richardson Mr. Book Bruce Spence Mr. Wall Colin Friels Det. Eddie Walenski John Bluthal Karl Harris Mitchell Butel Officer Husselbeck Melissa George May Frank Gallacher Chief Inspector Stromboli Ritchie Singer Hotel Manager / Vendor Justin Monjo Taxi Driver Nicholas Bell Mr. Rain Jeanette Cronin Stranger David Wenham Schreber's Assistant Paul Livingston Assistant Stranger Deobia Oparei Train Passenger Doug Scroope Desk Sergeant Laura Keneally Murdoch's Mum