Tom Cruise Barry Seal Sarah Wright Lucy Seal Domhnall Gleeson Monty Schafer Alejandro Edda Jorge Ochoa Jesse Plemons Sheriff Downing Connor Trinneer George W. Bush Mauricio Mejía Pablo Escobar Jayma Mays Dana Sibota Lola Kirke Judy Downing April Billingsley Jenny Jayson Warner Smith Bill Cooper William Mark McCullough Pete Dubois Lara Grice Female Reporter (uncredited) Frank Licari ATF Special Agent Franks Jed Rees Louis Finkle Caleb Landry Jones JB Benito Martinez James Rangel Justice Leak Agent Winter Sharon Conley DEA Agent Grace (uncredited) Mike Pniewski Willie Robert Pralgo Gary E. Roger Mitchell Agent Craig McCall Morgan Hinkleman Christina Seal Courtney Lakin Stewardess Chris Gann Donor #2 (uncredited) Tom Cruise Barry Seal Sarah Wright Lucy Seal Domhnall Gleeson Monty Schafer Alejandro Edda Jorge Ochoa Jesse Plemons Sheriff Downing Connor Trinneer George W. Bush Mauricio Mejía Pablo Escobar Jayma Mays Dana Sibota Lola Kirke Judy Downing April Billingsley Jenny Jayson Warner Smith Bill Cooper William Mark McCullough Pete Dubois Lara Grice Female Reporter (uncredited) Frank Licari ATF Special Agent Franks Jed Rees Louis Finkle Caleb Landry Jones JB Benito Martinez James Rangel Justice Leak Agent Winter Sharon Conley DEA Agent Grace (uncredited) Mike Pniewski Willie Robert Pralgo Gary E. Roger Mitchell Agent Craig McCall Morgan Hinkleman Christina Seal Courtney Lakin Stewardess Chris Gann Donor #2 (uncredited) Robert Farrior Oliver North Daniel Lugo Adolfo Calero Tom Cruise Barry Seal Sarah Wright Lucy Seal Domhnall Gleeson Monty Schafer Alejandro Edda Jorge Ochoa Jesse Plemons Sheriff Downing Connor Trinneer George W. Bush Mauricio Mejía Pablo Escobar Jayma Mays Dana Sibota Lola Kirke Judy Downing April Billingsley Jenny Jayson Warner Smith Bill Cooper William Mark McCullough Pete Dubois Lara Grice Female Reporter (uncredited) Frank Licari ATF Special Agent Franks Jed Rees Louis Finkle Caleb Landry Jones JB Benito Martinez James Rangel Justice Leak Agent Winter Sharon Conley DEA Agent Grace (uncredited) Mike Pniewski Willie Robert Pralgo Gary E. Roger Mitchell Agent Craig McCall Morgan Hinkleman Christina Seal Courtney Lakin Stewardess Chris Gann Donor #2 (uncredited) Robert Farrior Oliver North Daniel Lugo Adolfo Calero Lauren Boyd Secretary