Jason Schwartzman Augie Steenbeck / Jones Hall Scarlett Johansson Midge Campbell / Mercedes Ford Tom Hanks Stanley Zak Jeffrey Wright General Grif Gibson Tilda Swinton Dr. Hickenlooper Bryan Cranston The Host Edward Norton Conrad Earp Adrien Brody Schubert Green Liev Schreiber J.J. Kellogg Hope Davis Sandy Borden Stephen Park Roger Cho Rupert Friend Montana Maya Hawke June Douglas Steve Carell Motel Manager Matt Dillon Mechanic Hong Chau Polly Green Willem Dafoe Saltzburg Keitel Margot Robbie Actress / Wife Tony Revolori Aide-de-Camp Jake Ryan Woodrow Steenbeck Grace Edwards Dinah Campbell Aristou Meehan Clifford Sophia Lillis Shelly Ethan Josh Lee Ricky Cho Jeff Goldblum The Alien Jason Schwartzman Augie Steenbeck / Jones Hall Scarlett Johansson Midge Campbell / Mercedes Ford Tom Hanks Stanley Zak Jeffrey Wright General Grif Gibson Tilda Swinton Dr. Hickenlooper Bryan Cranston The Host Edward Norton Conrad Earp Adrien Brody Schubert Green Liev Schreiber J.J. Kellogg Hope Davis Sandy Borden Stephen Park Roger Cho Rupert Friend Montana Maya Hawke June Douglas Steve Carell Motel Manager Matt Dillon Mechanic Hong Chau Polly Green Willem Dafoe Saltzburg Keitel Margot Robbie Actress / Wife Tony Revolori Aide-de-Camp Jake Ryan Woodrow Steenbeck Grace Edwards Dinah Campbell Aristou Meehan Clifford Sophia Lillis Shelly Ethan Josh Lee Ricky Cho Jeff Goldblum The Alien Gracie Faris Pandora Ella Faris Andromeda Willan Faris Cassiopeia Bob Balaban Larkings Executive Fisher Stevens Detective #1 / Detective #2